Zu "371935-74-9" wurden 3 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
PI-103
Artikelnummer: Cay10009209-1
The phosphatidylinositol 3-kinases (PI3K) family of enzymes is comprised of 15 members that are divided into 3 classes according to their structure, substrate specificity, and mode of regulation. PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with...
| Schlagworte: | 3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]-phenol |
| Anwendung: | PI3K inhibitor |
| CAS | 371935-74-9 |
| MW: | 348.4 D |
ab 45,00 €
PI103
Artikelnummer: SYN-1065-M050
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. PI-103 is an isoform-selective class I PI3K and mTOR inhibitor. It has activity on p110alpha-delta with IC(50) values of 2nM, 3nM, 3nM, 15nM respectively. It is less potent against mTOR and DNA-PK with IC(50) values of 30nM and 23nM respectively. Target: PI3K...
| Schlagworte: | PI-103 |
| Anwendung: | PI3K / DNA-PK / mTOR inhibitor |
| CAS | 371935-74-9 |
| MW: | 348,4 D |
ab 146,00 €
PI-103
Artikelnummer: TGM-T6143-100mg
Description: PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110alpha/beta/delta/gamma, mTOR, and DNA-PK). Target: Apoptosis, Autophagy, mTOR, PI3K, DNA-PK. Smiles: Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1. References: Raynaud FI, et al....
| Schlagworte: | PI 103, PI103 |
| Anwendung: | PI3K inhibitor |
| CAS | 371935-74-9 |
| MW: | 348.36 D |
ab 49,00 €
