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MPP+ iodide
Artikelnummer: TGM-T9169-100mg
Description: MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin...
| CAS | 36913-39-0 |
| MW: | 297.13 D |
ab 34,00 €
MPP+ Iodide
Artikelnummer: Cay16958-50
MPP+ is an active metabolite of MPTP, a neurotoxin used to cause selective destruction of dopaminergic neurons in animal models of parkinsonism. MPP+ induces neurotoxicity primarily by inhibiting complex I of the mitochondrial electron transport chain, resulting in ATP depletion and increased oxidative stress. The...
| Schlagworte: | N-Methyl-4-Phenylpyridinium Iodide, 1-methyl-4-phenyl-pyridinium, monoiodide |
| Anwendung: | Neurotoxin, oxidative stress inducer |
| CAS | 36913-39-0 |
| MW: | 297.1 D |
ab 66,00 €
