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Ikarugamycin
Ikarugamycin

Artikelnummer: Cay15386-2.5

Ikarugamycin is a macrocyclic antibiotic first isolated from Streptomyces sp. that demonstrates potent antiprotozoal activity. It exhibits cytotoxic effects in cancer cell lines, inhibiting cell proliferation (IC50 = 221.3 nM in HL-60 cells) through genotoxicity and by inducing apoptosis and activation of caspases....
Schlagworte: (2R,3R,7Z,14S,19E)-3-ethyl-2,3,3aS,5aR,5bS,6,10,11,12,13,14,15,20aS,21,21aR,21bR-hexadecahydro-22-hydroxy-2-methyl-14,17-m...
Anwendung: Antibiotic
CAS 36531-78-9
MW: 478.6 D
ab 240,00 €
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Ikarugamycin
Ikarugamycin

Artikelnummer: LKT-I4000.1

An antiprotozoal antibiotic found to inhibit cholesteryl ester accumulation in macrophage. Shown to be efficient inhibitor of clathrin-coated pits-dependent endocytosis.
Anwendung: Antibiotic
CAS 36531-78-9
MW: 480,64 D
594,00 €
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Ikarugamycin
Ikarugamycin

Artikelnummer: I2300-20.500

Ikarugamycin is an unsual pentacyclic tetramic acid produced by Streptomyces phaeochromogenes with potent activity against the protozoan, Trichomonas vaginalis, reported in 1972. Ikarugamycin also demonstrated selective Gram positive antibacterial activity and more recently has been shown to exhibit anti-ulcer...
CAS 36531-78-9
MW: 478,6 D
488,00 €
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