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RBC8
Artikelnummer: Cay21281-5
RBC8 is a small molecule inhibitor of the Ras-like GTPases RalA and RalB that prevents binding of the GTPase to the Ral-binding protein. RBC8 has been shown to prevent Ral-mediated spreading of murine embryonic fibroblasts, block anchorage-independent growth of H2122 and H358 lung cancer cell lines (IC50s = 3.5 and...
| Schlagworte: | 6-amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)-pyrano[2,3-c]pyrazole-5-carbonitrile |
| Anwendung: | RalA / RalB inhibitor |
| CAS | 361185-42-4 |
| MW: | 424.5 D |
ab 57,00 €
RBC8
Artikelnummer: TGM-T6634-100mg
Description: RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras. Target: Ras, GTPase. Smiles: COc1ccc(OC)c(c1)C1c2c(OC(N)=C1C#N)[nH]nc2-c1ccc2ccccc2c1. References: Yan C, et al. Nature. 2014, 515(7527), 443-447.
| Anwendung: | RalA / RalB inhibitor |
| CAS | 361185-42-4 |
| MW: | 424.45 D |
ab 39,00 €
