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NNC 55-0396
Artikelnummer: TGM-T12238-100mg
Description: NNC 55-0396 is a highly selective T-type calcium channel blocker with an IC50 of 6.8 µM, used in studies to prevent human ovarian cancer cell proliferation. Target: Calcium Channel. Smiles: Cl.Cl.CC(C)C1c2ccc(F)cc2CCC1(CCN(C)CCCc1nc2ccccc2[nH]1)OC(=O)C1CC1. References: Timo Strünker, Normann Goodwin,...
| Schlagworte: | NNC 55-0396 dihydrochloride |
| CAS | 357400-13-6 |
| MW: | 564.56 D |
ab 60,00 €
NNC 55-0396
Artikelnummer: Cay17216-1
NNC 55-0396 is a selective inhibitor of T-type calcium channels that blocks Cav3.1 in stably expressing HEK293 cells (IC50 = 6.8 µM) with no discernible effect on high voltage-activated (L-type) channels in INS-1 cells up to a concentration of 100 µM. NNC 55-0396 suppresses tremor in two murine models, the GABAA...
| Schlagworte: | cyclopropanecarboxylic acid,... |
| CAS | 357400-13-6 |
| MW: | 564.6 D |
ab 69,00 €
