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HC-030031
Artikelnummer: TGM-T6530-100mg
Description: HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2±0.2 and 5.3±0.2 µM, respectively. Target: TRP/TRPV Channel. Smiles: CC(C)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1. References: McNamara CR, et al. Proc Natl Acad Sci,...
| Schlagworte: | TOSLAB 829227, HC030031 |
| Anwendung: | TRPA1 blocker |
| CAS | 349085-38-7 |
| MW: | 355.39 D |
ab 46,00 €
HC-030031
Artikelnummer: Cay11923-50
Transient receptor potential cation channel A1 (TRPA1) is an ankyrin-like ion channel which acts as a sensor for chemical irritants, pain, and cold. It is activated by allyl isothiocyanate (AITC), formalin, hydrogen peroxide, tear gas, and other compounds. HC-030031 is a selective TRPA1 blocker, antagonizing...
| Schlagworte: | 1,2,3,6-tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide |
| Anwendung: | TRPA1 blocker |
| CAS | 349085-38-7 |
| MW: | 355.4 D |
ab 38,00 €
