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UK 383367
Artikelnummer: Cay15029-25
UK 383367 is a potent inhibitor of bone morphogenetic protein 1 (BMP1, IC50 = 44 nM). It is more than 200-fold selective for BMP1 over a panel of matrix metalloproteinases. UK 383367 is effective in a cell-based model of collagen deposition is very effective at penetrating human skin in vitro.Formal Name:...
| Schlagworte: | (betaR)-3-(aminocarbonyl)-beta-(3-cyclohexylpropyl)-N-hydroxy-1,2,4-oxadiazole-5-propanamide |
| Anwendung: | BMP-1 inhibitor |
| CAS | 348622-88-8 |
| MW: | 324.4 D |
ab 49,00 €
UK-383367
Artikelnummer: TGM-T6064-10mg
Description: UK-383367 is a procollagen C-proteinase inhibitor with IC50 of 44 nM, has excellent selectivity over MMPs. Target: Procollagen C Proteinase. Smiles: NC(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO. References: Fish PV, et al. J Med Chem, 2007, 50(15), 3442-3456.
| Schlagworte: | UK 383367 |
| Anwendung: | BMP-1 inhibitor |
| CAS | 348622-88-8 |
| MW: | 324.38 D |
ab 46,00 €
