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Sunitinib (malate)
Sunitinib (malate)

Artikelnummer: Cay13159-1

Sunitinib is a small molecule inhibitor of receptor tyrosine kinases, including FLK1 (Ki = 9 nM), PDGFRbeta (Ki = 8 nM), and FLT3. It is at least 10-fold selective for FLK1 and PDGFRbeta over a variety of tyrosine kinases in a panel, including EGFR, Cdk2, Met, IGFR-1, Abl, and Src. Sunitinib inhibits VEGF-dependent...
Schlagworte: SU11248,...
Anwendung: Receptor tyrosine kinase inhibitor
CAS 341031-54-7
MW: 532.6 D
ab 45,00 €
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Sunitinib Malate
Sunitinib Malate

Artikelnummer: TGM-T0374-50mg

Description: Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRbeta (IC50: 80/2 nM), and c-kit. Target: VEGFR, c-Kit, Autophagy, FLT, PDGFR, IRE1, Apoptosis, Mitophagy. Smiles:...
Schlagworte: SU 11248 (Malate), Sutent, SU 11248, Sunitinib
CAS 341031-54-7
MW: 532.56 D
ab 36,00 €
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Sunitinib Maleate (Sutent)
Sunitinib Maleate (Sutent)

Artikelnummer: S8032.100

A multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Sunitinib and its active metabolite (SU012662) are selective inhibitors of multiple receptor tyrosine kinases, including platelet-derived growth factor receptor and vascular endothelial growth factor receptor, that are associated with tumor...
CAS 341031-54-7
ab 142,00 €
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Sunitinib . malate
Sunitinib . malate

Artikelnummer: AG-CR1-3707-M001

Potent ATP-competitive and cell permeable multi-targeted receptor tyrosine kinase (RTK) inhibitor targeting VEGFR and PDGFR-beta. Inhibits FLK1 (Ki=9nM), PDGFRbeta (Ki=8nM) and FLT3. It is at least 10-fold selective for FLK1 and PDGFRbeta over a variety of tyrosine kinases in a panel, including EGFR, Cdk2, Met,...
Schlagworte: SU-11248
Anwendung: Potent cell permeable multi-targeted receptor tyrosine kinase (VEGFR, PDGFR-beta) inhibitor
CAS 341031-54-7
MW: 532.6 D
ab 33,00 €
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