Zu "339068-25-6" wurden 2 Artikel gefunden!
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HET0016
Artikelnummer: Cay75780-10
20-HETE is a major biologically active cytochrome P450 (CYP450) metabolite of arachidonic acid in the kidney and liver. It regulates renal vascular and tubular functions as well as vascular tone in the cerebral circulation. HET0016 is an inhibitor of 20-HETE formation in human renal microsomes with an IC50 of 8.9...
| Schlagworte: | N-hydroxy-N'-(4-n-butyl-2-methylphenyl)Formamidine, N-(4-butyl-2-methylphenyl)-N'-hydroxy-methanimidamide |
| Anwendung: | Bioactive lipid assays |
| CAS | 339068-25-6 |
| MW: | 206.3 D |
ab 24,00 €
HET0016
Artikelnummer: TGM-T11556-1mg
Description: HET0016 is a potent and selective 20-HETE synthase inhibitor (IC50s: 17.7 nM, 12.1 nM, and 20.6 nM for recombinant CYP4A1-, CYP4A2-, and CYP4A3-catalyzed 20-HETE synthesis) and a selective CYP450 inhibitor, shown to inhibit angiogenesis and tumor growth. Target: Others. Smiles: CCCCc1ccc(N=CNO)c(C)c1....
| CAS | 339068-25-6 |
| MW: | 206.28 D |
ab 30,00 €
