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CITCO
Artikelnummer: Cay16027-10
CITCO is an agonist of human CAR (EC50 = 49 nM). It induces nuclear translocation of human CAR in hepatocytes, followed by increased expression of CAR-regulated genes, including several cytochrome P450 isoforms. CITCO less potently activates human pregnane X receptor (EC50 = 3 µM) and has no detectable activity on...
| Schlagworte: | O-[(3,4-dichlorophenyl)methyl]oxime 6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carboxaldehyde |
| Anwendung: | CAR agonist |
| CAS | 338404-52-7 |
| MW: | 436.7 D |
ab 108,00 €
CITCO
Artikelnummer: TGM-T14973-100mg
Description: CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO is an imidazothiazole derivative and it also is a selective Constitutive androstane receptor (CAR) agonist. Target: Apoptosis,...
| Anwendung: | CAR agonist |
| CAS | 338404-52-7 |
| MW: | 436.74 D |
ab 54,00 €
