Zu "333994-00-6" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
TAK-220
Artikelnummer: Cay28448-1
TAK-220 is an orally bioavailable antagonist of chemokine (C-C motif) receptor 5 (CCR5). It binds to CCR5 (IC50 = 3.5 nM for the human receptor in CHO cells), but not CCR1, CCR2b, CCR3, CCR4, or CCR7. TAK-220 inhibits the binding of chemokine (C-C motif) ligand 5 (CCL5) and CCL3 to CCR5 (IC50s = 3.5 and 1.4 nM,...
| Schlagworte: | 1-acetyl-N-[3-[4-[[4-(aminocarbonyl)phenyl]methyl]-1-piperidinyl]propyl]-N-(3-chloro-4-methylphenyl)-4-piperidinecarboxamide |
| Anwendung: | CCR5 antagonist |
| CAS | 333994-00-6 |
| MW: | 553.1 D |
235,00 €
TAK-220
Artikelnummer: TGM-T16973-100mg
Description: TAK-220 is a selective and orally bioavailable CCR5 antagonist with IC50 values of 3.5 nM for RANTES binding inhibition and 1.4 nM for MIP-1alpha binding inhibition to CCR5. Target: HIV Protease. Smiles: CC(=O)N1CCC(CC1)C(=O)N(CCCN1CCC(Cc2ccc(cc2)C(N)=O)CC1)c1ccc(C)c(Cl)c1. References: Takashima K, et...
| Anwendung: | CCR5 antagonist |
| CAS | 333994-00-6 |
| MW: | 553.14 D |
ab 327,00 €
