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LX2343
Artikelnummer: Cay27799-1
LX2343 is an inhibitor of beta-site amyloid protein cleaving enzyme 1 (BACE1/beta-secretase, IC50 = 11.43 µM) and PI3K (IC50 = 15.99 µM). It inhibits accumulation of Abeta (1-40) (Abeta40) and Abeta42 induced by streptozotocin (STZ, Cay-13104) in both HEK293-APPSW and CHO-APP cells, which express mutant and...
| Schlagworte: | N-1,3-benzodioxol-5-yl-2-[(5-chloro-2-methoxyphenyl)(phenylsulfonyl)amino]-acetamide |
| Anwendung: | BACE1 inhibitor |
| CAS | 333745-53-2 |
| MW: | 474.9 D |
ab 73,00 €
LX-2343
Artikelnummer: LKT-L920000.100
| Schlagworte: | LX2343 |
| Anwendung: | BACE1 inhibitor |
| CAS | 333745-53-2 |
| MW: | 474.91 D |
ab 141,00 €
LX2343
Artikelnummer: TGM-T4398-100mg
Description: LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 µM and acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 µM. Additionally, LX2343 stimulates autophagy, promoting Abeta clearance. Target: Beta-Secretase, Beta Amyloid, PI3K, Autophagy, BACE. Smiles:...
| Anwendung: | BACE1 inhibitor |
| CAS | 333745-53-2 |
| MW: | 474.91 D |
ab 30,00 €
