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Avanafil
Artikelnummer: Cay23024-100
Avanafil is an orally bioavailable, potent, and competitive inhibitor of phosphodiesterase (PDE) 5 (IC50 = 2.2 nM). It is selective, with IC50 values of 630, >5,000, and >5,000 nM for PDE6, PDE1-4, and PDE7-11, respectively, in an enzyme assay. Avanafil potentiates penile tumescence in dogs in a dose-dependent...
| Schlagworte: | TA-1790,... |
| Anwendung: | PDE5 inhibitor |
| CAS | 330784-47-9 |
| MW: | 484 D |
ab 49,00 €
Avanafil
Artikelnummer: TGM-T2334-1mL
Description: Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction. Target: NO Synthase, PDE, Endogenous Metabolite. Smiles: C(O)[C@H]1N(C=2N=C(NCC3=CC(Cl)=C(OC)C=C3)C(C(NCC=4N=CC=CN4)=O)=CN2)CCC1
| Schlagworte: | TA1790 |
| Anwendung: | Targets cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35] (PDE5) |
| CAS | 330784-47-9 |
| MW: | 483.95 D |
ab 29,00 €
