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4E1rcat
Artikelnummer: TGM-T1742-100mg
Description: 4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 µM. Target: PERK, Autophagy. Smiles: OC(=O)c1ccc(cc1)N1C(=O)\C(=C\c2ccc(o2)-c2ccc(cc2)[N+]([O-])=O)C=C1c1ccccc1. References: Shuda M, et al. Proc Natl Acad Sci U S...
| Anwendung: | Protein translation inhibitor, eIF4E:eIF4G & eIF4E:4E-BP1 interaction inhibitor |
| CAS | 328998-25-0 |
| MW: | 478.45 D |
ab 46,00 €
4E1RCat
Artikelnummer: Cay18399-1
4E1RCat is an inhibitor of the eIF4F translation initiation complex that blocks eIF4E:eIF4G and eIF4E:4E-BP1 interactions. It has been shown to prevent the assembly of the eIF4F complex and to inhibit cap-dependent translation with an IC50 value of ~4 µM. 4E1RCat was shown to reverse tumor chemoresistance in a mouse...
| Schlagworte: | eIF4E/eIF4G Interaction Inhibitor II,... |
| Anwendung: | Protein translation inhibitor, eIF4E:eIF4G & eIF4E:4E-BP1 interaction inhibitor |
| CAS | 328998-25-0 |
| MW: | 478.5 D |
ab 52,00 €
