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ICA 110381
Artikelnummer: Cay37294-10
ICA 110381 is an activator of voltage-gated potassium channel Kv7.2. It induces rubidium efflux in an agonist-induced rubidium efflux assay using CHO cells (EC50 = 0.38 µM for the human channel). ICA 110381 also inhibits rubidium efflux from CHO cells expressing Kv7.1 (EC50 = 15 µM for the human channel). It reduces...
| Schlagworte: | 4-chloro-N-(6-chloro-3-pyridinyl)-benzamide |
| Anwendung: | Kv7.2 (KCNQ2) activator |
| CAS | 325457-99-6 |
| MW: | 267.1 D |
ab 75,00 €
ICA 110381
Artikelnummer: TGM-T7612-100mg
Description: ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy. Target: Potassium Channel. Smiles: C(NC=1C=CC(Cl)=NC1)(=O)C2=CC=C(Cl)C=C2. References: Amato G , Roeloffs R , Rigdon G C , et al. N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment...
| Anwendung: | Kv7.2 (KCNQ2) activator |
| CAS | 325457-99-6 |
| MW: | 267.11 D |
ab 30,00 €
