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PHPS1
Artikelnummer: TGM-T28410-100mg
Description: PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines. Target: Phosphatase. Smiles:...
| Schlagworte: | PHPS-1, PHPS 1 |
| Anwendung: | SHP-2 inhibitor, cell-permeable, phosphotyrosine mimetic |
| CAS | 314291-83-3 |
| MW: | 465.44 D |
ab 40,00 €
PHPS1
Artikelnummer: Cay18856-1
PHPS1 is a cell-permeable, phosphotyrosine mimetic that inhibits the Src homology region 2 domain-containing phosphatase (SHP)-2 (IC50 = 2.1 µM, Ki = 0.73 µM). It is selective for SHP-2, inhibiting ECPTP, PTP1B, SHP-1, and mycobacterium MptpA at relatively higher concentrations (IC50s = 5.4, 19, 30, and 39 µM,...
| Schlagworte: | Phenylhydrazonopyrazolone sulfonate 1, Protein Tyrosine Phosphatase Inhibitor V, PTP Inhibitor V,... |
| Anwendung: | SHP-2 inhibitor, cell-permeable, phosphotyrosine mimetic |
| CAS | 314291-83-3 |
| MW: | 465.4 D |
ab 55,00 €
