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THIQ
Artikelnummer: Cay24303-1
THIQ is a melanocortin 4 receptor (MC4R) agonist that is selective over MC1R, MC3R, and MC5R human receptors expressed in CHO cells (IC50s = 1.2, 2,067, 761, and 326 nM, respectively). It selectively increases cAMP accumulation in CHO cells expressing human MC4R over MC1R, MC3R, and MC5R (EC50s = 2.1, 2,850, 2,487,...
| Schlagworte: | (3R)-N-[(1R)-1-[(4-chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4... |
| Anwendung: | MC4R agonist |
| CAS | 312637-48-2 |
| MW: | 589.2 D |
ab 68,00 €
THIQ
Artikelnummer: TGM-T8485-10mg
Description: THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively). Target: Melanocortin Receptor. Smiles: ClC1=CC=C(C[C@@H](NC(=O)[C@H]2CC3=CC=CC=C3CN2)C(=O)N2CCC(CN3C=NC=N3)(CC2)C2CCCCC2)C=C1. References: Huang H, et al. A small molecule agonist...
| Anwendung: | MC4R agonist |
| CAS | 312637-48-2 |
| MW: | 589.17 D |
ab 46,00 €
