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Sphingosine Kinase Inhibitor 2
Sphingosine Kinase Inhibitor 2

Artikelnummer: Cay10009222-5

Sphingosine kinase isoforms, SPHK 1 and SPHK 2 , catalyze the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 is an...
Schlagworte: SKI II, SPHK I2, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-phenol
Anwendung: SPHK1 inhibitor
CAS 312636-16-1
MW: 302.8 D
ab 55,00 €
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SKI II
SKI II

Artikelnummer: TGM-T6673-100mg

Description: SKI II (SphK-I2) is a highly selective and non-ATP-competitive S1P receptor inhibitor (IC50: 0.5 µM) while exhibiting no inhibitory action on other kinases including PKCalpha, PI3K, and ERK2. Target: Wnt/beta-catenin, Apoptosis, S1P Receptor. Smiles: Oc1ccc(Nc2nc(cs2)-c2ccc(Cl)cc2)cc1. References:...
Schlagworte: SphK-I2
Anwendung: SPHK1 inhibitor
CAS 312636-16-1
MW: 302.78 D
ab 34,00 €
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