Zu "31083-55-3" wurden 2 Artikel gefunden!
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PRT4165
Artikelnummer: Cay19093-10
BMI1/RING1A and BMI1/RNF2 are E3 ubiquitin ligase complexes that mediate the monoubiquitination of histone 2A (H2A). This is an essential function of polycomb repressive complex 1 (PRC1). PRT4165 is an inhibitor of the ubiquitin ligase activity of PRC1. It blocks BMI1/RING1A self-ubiquitination (IC50 = 3.9 µM), as...
| Schlagworte: | NSC 600157, 2-(3-pyridinylmethylene)-1H-indene-1,3(2H)-dione |
| Anwendung: | BMI1/RING1A & BMI1/RNF2 inhibitor |
| CAS | 31083-55-3 |
| MW: | 235.2 D |
ab 85,00 €
PRT4165
Artikelnummer: TGM-T3110-100mg
Description: PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor. Target: Others, BMI-1, E1/E2/E3 Enzyme. Smiles: O=C1C(=Cc2cccnc2)C(=O)c2ccccc12. References: Ismail, et al. J Biol Chem. 2013 Sep 13,288(37):26944-54.
| Schlagworte: | NSC600157, PRT 4165 |
| Anwendung: | BMI1/RING1A & BMI1/RNF2 inhibitor |
| CAS | 31083-55-3 |
| MW: | 235.24 D |
ab 37,00 €
