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SCIO 469
Artikelnummer: Cay29484-1
SCIO 469 is a p38 MAPK inhibitor (IC50 = 9 nM for p38alpha). It is 10-fold selective for p38alpha over p38beta MAPK and 2,000-fold selective over a panel of 20 additional kinases. SCIO 469 inhibits secretion of IL-6 from multiple myeloma patient-derived bone marrow stromal cells (BMSCs) in a concentration-dependent...
| Schlagworte: | Talmapimod,... |
| Anwendung: | p38 MAPK inhibitor |
| CAS | 309913-83-5 |
| MW: | 513 D |
ab 53,00 €
Talmapimod
Artikelnummer: TGM-T12871-100mg
Description: Talmapimod (SCIO-469) is a selective, orally active, ATP-competitive p38alpha inhibitor with IC50 values of 9 nM for p38alpha and 90 nM for p38beta. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs. Target: p38 MAPK. Smiles:...
| Schlagworte: | SCIO-469 |
| Anwendung: | Targets p38 MAP kinase [EC:2.7.11.24] (P38) |
| CAS | 309913-83-5 |
| MW: | 513 D |
ab 46,00 €
