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SC-79
Artikelnummer: Cay14972-10
SC-79 is an activator of Akt that blocks its membrane translocation while allowing its phosphorylation, in the cytosol, by upstream kinases. For example, both Thr308 and Ser473 on Akt are phosphorylated in serum starved HeLa cells treated for 1 hour with insulin growth factor and SC-79 (4 µg/ml). SC-79 permits...
| Schlagworte: | 2-amino-6-chloro-alpha-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid, ethyl ester |
| Anwendung: | Akt activator |
| CAS | 305834-79-1 |
| MW: | 364.8 D |
ab 89,00 €
SC79
Artikelnummer: TGM-T2274-100mg
Description: SC79 is an AKT agonist with specificity and blood-brain barrier permeability. SC79 specifically binds to the PH domain of AKT, activates cytoplasmic AKT, and inhibits AKT membrane translocation. SC79 has neuroprotective activity. Target: Akt. Smiles: CCOC(=O)C(C#N)C1C(C(=O)OCC)=C(N)Oc2ccc(Cl)cc12....
| Schlagworte: | SC 79 |
| Anwendung: | Akt activator |
| CAS | 305834-79-1 |
| MW: | 364.78 D |
ab 49,00 €
