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PD 173952
Artikelnummer: Cay45469-1
A multi-kinase inhibitor, inhibits LYN, Abl, CSK, and c-Src in cell-free assays (IC50s = 0.3, 1.7, 6.6, and 8.5 nM, respectively), inhibits growth of HCT-8, SW620 and HT-29 cells (IC50s = 1.53, 1.8, and 0.526 µM, respectively), induces cell cycle arrest at the G2/M phase in HT-29 cells when at 1 µM, induces...
| Schlagworte: | 6-(2,6-dichlorophenyl)-8-methyl-2-[[4-(4-morpholinyl)phenyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one |
| Anwendung: | Multi-kinase inhibitor |
| CAS | 305820-75-1 |
| MW: | 482.37 D |
ab 39,00 €
PD173952
Artikelnummer: TGM-T24602-25mg
Description: PD173952 is an inhibitor of Src family kinase. Target: Others. Smiles: O=C1C(=CC=2C(N1C)=NC(NC3=CC=C(C=C3)N4CCOCC4)=NC2)C5=C(Cl)C=CC=C5Cl. References: Wichapong K, Rohe A, Platzer C, Slynko I, Erdmann F, Schmidt M, Sippl W. Application of docking and QM/MM-GBSA rescoring to screen for novel Myt1 kinase...
| Schlagworte: | PD 173952, PD-173952 |
| CAS | 305820-75-1 |
| MW: | 482.36 D |
ab 594,00 €
