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UNC9426
Artikelnummer: Cay44849-1
UNC9426 is an inhibitor of the TAM family kinase Tyro3 (IC50 = 2. nM). It is selective for Tyro3 over MerTK and Axl (IC50s = 580 and 190 nM, respectively) and 74 other kinases in a panel at 1 µM. UNC9426 (10 µM) reduces ADP- or collagen-induced platelet aggregation in isolated human platelet-rich plasma. It does not...
| Schlagworte: | trans-4-[2-[[3,5-bis(trifluoromethyl)phenyl]amino]-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin... |
| Anwendung: | Tyro3 inhibitor |
| CAS | 3051784-94-9 |
| MW: | 632.66 D |
ab 83,00 €
