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AVE 0991
AVE 0991

Artikelnummer: TGM-TQ0057-10mg

Description: AVE 0991, a nonpeptide analog of angiotensin-(1-7) [Ang-(1-7)], is an orally active Mas agonist with inhibitory effects on [125I]-Ang-(1-7) binding to bovine aortic endothelial cell membranes, and inhibits astrocyte-mediated neuroinflammation in Alzheimer's disease by enhancing autophagy. Target:...
Anwendung: Mas receptor agonist
CAS 304462-19-9
MW: 580.72 D
ab 81,00 €
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AVE-0991
AVE-0991

Artikelnummer: Cay37837-1

AVE-0991 is an agonist of the Mas receptor, also known as the angiotensin (1-7) receptor. It binds to the Mas receptor in bovine aortic endothelial cell membranes and COS cells (IC50s = 21 and 47.5 nM, respectively). It reduces urinary volume in water-loaded mice, an effect that can be blocked by the angiotensin...
Schlagworte: N-[(ethylamino)carbonyl]-3-[4-[(5-formyl-4-methoxy-2-phenyl-1H-imidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)-2-thiophene...
Anwendung: Mas receptor agonist
CAS 304462-19-9
MW: 580.7 D
ab 70,00 €
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