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OX04528
Artikelnummer: Cay42377-10
A G protein-biased agonist of GPR84, inhibits forskolin-induced cAMP production in CHO cells expressing human GPR84 (EC50 = 0.00598 nM), does not induce ß-arrestin recruitment at concentrations up to 80 µM. Formulation: A solid. InChI:...
| Schlagworte: | 5-[3-[3,5-bis(trifluoromethyl)phenyl]propyl]-3-pyridinol, 1-oxide |
| Anwendung: | GPR84 G protein-biased agonist |
| CAS | 3028055-45-7 |
| MW: | 365.27 D |
ab 116,00 €
OX04528
Artikelnummer: TGM-T84313-100mg
Description: OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research. Target: GPR, cAMP. Smiles: OC1=C[N+]([O-])=CC(CCCC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=C1. References: Wang P, et al. Development of Highly Potent, G-Protein Pathway Biased,...
| CAS | 3028055-45-7 |
| MW: | 365.27 D |
ab 183,00 €
