Zu "301692-76-2" wurden 2 Artikel gefunden!
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Polmacoxib
Artikelnummer: Cay17509-1
Polmacoxib is an inhibitor of cyclooxygenase 2 (COX-2) and the carbonic anhydrase subtypes I (CAI) and CAII. It inhibits COX-2 in the absence of carbonic anhydrase II with an IC50 value of 40 nM, which increases by approximately 4- and 17-fold in the presence of a CAII at a molar ratio of 1:1 and 1:5, respectively....
| Schlagworte: | 4-[3-(3-fluorophenyl)-4,5-dihydro-5,5-dimethyl-4-oxo-2-furanyl]-benzenesulfonamide |
| Anwendung: | COX-2 inhibitor |
| CAS | 301692-76-2 |
| MW: | 361.4 D |
ab 89,00 €
Polmacoxib
Artikelnummer: TGM-T21294-100mg
Description: Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation. Target: Carbonic Anhydrase, COX. Smiles:...
| Schlagworte: | CG100649, CG 100649, CG-100649 |
| CAS | 301692-76-2 |
| MW: | 361.39 D |
ab 38,00 €
