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FLT3 Inhibitor
Artikelnummer: Cay18462-10
Fms-like tyrosine kinase (FLT3) is a cell-surface receptor with important roles in stem cell development, hematopoiesis, and cancer. FLT3 Inhibitor is a cell-permeable, ATP-competitive inhibitor of FLT3 (IC50 = 27 nM) that blocks the proliferation of myelomonocytic leukemia MV4-11 cells (IC50 = 0.41 µM). It is...
| Schlagworte: | Fms-like Tyrosine Kinase Inhibitor, TCS 359,... |
| Anwendung: | CD135 inhibitor |
| CAS | 301305-73-7 |
| MW: | 360.4 D |
ab 93,00 €
TCS 359
Artikelnummer: TGM-T6138-100mg
Description: TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM. Target: FLT. Smiles: COc1ccc(cc1OC)C(=O)Nc1sc2CCCCc2c1C(N)=O. References: Raymond J. Patch, et al. Bioorg Med Chem Lett, 2006, 16(12), 3282-3286.
| Schlagworte: | FLT3 Inhibitor |
| Anwendung: | CD135 inhibitor |
| CAS | 301305-73-7 |
| MW: | 360.43 D |
ab 30,00 €
