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PROTAC EGFR Degrader 9
Artikelnummer: Cay45393-1
A PROTAC that drives mutant EGFR degradation, selectively induces degradation of mutant EGFRs over wild-type EGFR (DC50s = 10.2, 36.5, 88.5, 75.4, and >300 nM for EGFRL858R/T790M/C797S, EGFRDelta19/T790M/C797S, EGFRL858R/T790M, EGFRDelta19, and wild-type EGFR, respectively), inhibits the growth of H1975 cells...
| Schlagworte: | Proteolysis-targeting Chimera EGFR Degrader-9, Proteolysis-targeting Chimera Epidermal Growth Factor Receptor Degrader-9,... |
| Anwendung: | Mutant EGFR degradation driving PROTAC |
| CAS | 2992670-33-2 |
| MW: | 899.99 D |
ab 271,00 €
