Zu "294646-77-8" wurden 5 Artikel gefunden!
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(R)-CR8
Artikelnummer: Cay14006-10
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. (R)-CR8 is a second-generation analog of (R)-roscovitine (Cay-10009569) that inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk9/cyclin T with IC50 values of 0.09,...
| Schlagworte: | 2R-[[9-(1-methylethyl)-6-[[[4-(2-pyridinyl)phenyl]methyl]amino]-9H-purin-2-yl]amino]-1-butanol |
| Anwendung: | CDK Inhibitor |
| CAS | 294646-77-8 |
| MW: | 431.5 D |
ab 77,00 €
(R)-CR8
Artikelnummer: AG-CR1-0039-M001
Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor, Apoptosis inducer, Potent glycogen synthase kinase (GSK-3alpha/beta) inhibitor.
| Schlagworte: | 2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-(4-(2-pyridyl)benzyl)-9-isopropylpurine |
| Anwendung: | CDK inhibitor |
| CAS | 294646-77-8 |
| MW: | 431,5 D |
ab 50,00 €
(S)-CR8
Artikelnummer: AG-CR1-0040-M005
Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor, Apoptosis inducer, Glycogen synthase kinase (GSK-3alpha/beta) inhibitor.
| Schlagworte: | 2-(S)-(1-Ethyl-2-hydroxyethylamino)-6-(4-(2-pyridyl)benzyl)-9-isopropylpurine |
| Anwendung: | CDK inhibitor |
| CAS | 294646-77-8 |
| MW: | 431,5 D |
ab 50,00 €
(R)-CR8
Artikelnummer: AG-MR-C0003-M010
Soluble in DMSO or ethanol. Stock solutions can be made up to 10 mM in DMSO. Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5, CDK7 and CDK9. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Casein kinase 1 (CK1delta/epsilon) and glycogen synthase kinase...
| Schlagworte: | 2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-(4-(2-pyridyl)benzyl)-9-isopropylpurine |
| Anwendung: | Cyclin dependent kinase inhibitor |
| CAS | 294646-77-8 |
| MW: | 431,5 D |
ab 286,00 €
(R)-CR8
Artikelnummer: LKT-C6800.1
Roscovitine analog, CDK inhibitor.
| Schlagworte: | 2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-(4-(2-pyridyl)benzyl)-9-isopropylpurine |
| Anwendung: | Roscovitine analog, CDK inhibitor |
| CAS | 294646-77-8 |
| MW: | 431.54 D |
ab 187,00 €
