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NEU
BI-2493
Artikelnummer: Cay44474-1
BI-2493 is an inhibitor of mutant K-Ras. It selectively decreases the proliferation of Ba/F3 cells expressing K-Ras containing a glycine-to-cysteine substitution at position 12 (K-RasG12C), K-RasG12D, or K-RasG12V (EC50s = 118, 52, and 81 nM, respectively) over Ba/F3 cells expressing H-Ras or N-Ras (EC50s = 2,359...
| Schlagworte: | (4'S)-2'-amino-5,6,6',7'-tetrahydro-3-[2-[(2S)-2-methyl-1-piperazinyl]-4-pyrimidinyl]-spiro[1,2-benzisoxazole-7(4H),4'(5'H... |
| Anwendung: | Mutant K-Ras inhibitor |
| CAS | 2937344-16-4 |
| MW: | 461.59 D |
ab 88,00 €
BI-2493
Artikelnummer: TGM-T72061-10mg
Description: BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.BI-2493 exhibits antitumor activity and inhibits tumor cell growth and can be used in the study of cancerous diseases.BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865. Target: Ras. Smiles:...
| CAS | 2937344-16-4 |
| MW: | 461.58 D |
ab 595,00 €
