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Canertinib (hydrochloride)
Artikelnummer: Cay12076-5
The HER family of receptor tyrosine kinases, EGFR, HER2, HER3, and HER4, mediate proliferation, migration, adhesion, differentiation, and survival in many different cell types and have been implicated in the development and progression of a variety of human tumors. Canertinib is an irreversible quinazoline-based HER...
| Schlagworte: | CI-1033, PD 183805, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide,... |
| Anwendung: | EGFR tyrosine kinase inhibitor |
| CAS | 289499-45-2 |
| MW: | 558.9 D |
ab 56,00 €
![Canertinib, Dihydrochloride (N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-qu](https://www.biomol.com/media/image/0b/bd/78/C1075-25-25_200x200.jpg "Canertinib, Dihydrochloride (N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-qu")
Canertinib, Dihydrochloride...
Artikelnummer: C1075-25.25
Canertinib (CI-1033, PD 183805) is a pan-erbB tyrosine kinase inhibitor. It selectively inhibits erbB1 (epidermal growth factor receptor), erbB2, erbB3, and erbB4 without blocking tyrosine kinase activity of many other receptors such as platelet-derived growth factor receptor, fibroblast growth factor receptor, and...
| CAS | 289499-45-2 |
| MW: | 558.86 |
236,00 €
Canertinib Dihydrochloride
Artikelnummer: LKT-C0252.100
A water-soluble, EGFR tyrosine kinase inhibitor. It induces ErbB-independent apoptosis in human leukemia (HL-60 and U937) cells.
| Schlagworte: | CI1033 |
| Anwendung: | EGFR tyrosine kinase inhibitor |
| CAS | 289499-45-2 |
| MW: | 558,86 D |
ab 187,00 €
Canertinib dihydrochloride
Artikelnummer: TGM-T2501-10mg
Description: Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. Target: Virus Protease, EGFR. Smiles: Cl.Cl.Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl
| Schlagworte: | CI-1033 dihydrochloride , PD-183805 dihydrochloride |
| Anwendung: | Targets epidermal growth factor receptor [EC:2.7.10.1] (EGFR, ERBB1) |
| CAS | 289499-45-2 |
| MW: | 558.86 D |
ab 30,00 €
