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JAK Inhibitor 31
Artikelnummer: Cay39387-1
JAK inhibitor 31 is an inhibitor of JAK2 (IC50 = 3.9 nM). It is selective for JAK2 over JAK3 (IC50s = 70 nM), as well as Aurora B kinase, VEGFR2, Abl1, and GSK3beta (IC50s = 0.441, 1.5, 21.37, and 50 µM, respectively), but does inhibit JAK1 and TYK2 (IC50s = 7 and 2.9 nM, respectively). JAK inhibitor 31 inhibits...
| Schlagworte: | Janus-Associated Kinase Inhibitor 31,... |
| Anwendung: | JAK2 inhibitor |
| CAS | 2891469-99-9 |
| MW: | 398.5 D |
ab 78,00 €
JAK-IN-30
Artikelnummer: TGM-T79235-10mg
Description: JAK-IN-30 (compound 31) is a water-soluble Janus kinase (JAK) inhibitor with IC50 values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, and 2 nM for TYK2, identified for its research potential in treating dry eye disease (DED) [1]. Target: JAK
| Anwendung: | JAK2 inhibitor |
| CAS | 2891469-99-9 |
| MW: | 398.53 D |
ab 168,00 €
