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JG-2016
Artikelnummer: TGM-T82008-100mg
Description: JG-2016, as a small molecule histone acetyltransferase 1 (HAT1) inhibitor, inhibits the growth of human cancer cell lines, inhibits enzyme activity in cellulose, and interferes with tumor growth. Target: Histone Acetyltransferase. Smiles: O=C1N=C2C(=NC=3C=C(Cl)C(=CC3N2CCOCC(C)C)CC)C(=O)N1. References:...
| CAS | 2887480-87-5 |
| MW: | 376.84 D |
ab 111,00 €
JG-2016
Artikelnummer: Cay41876-1
JG-2016 is an inhibitor of histone acetyltransferase 1 (HAT1, IC50 = 14.8 µM). It is selective for HAT1 over lysine acetyltransferase 2A (KAT2A/GCN5) and p300/CBP-associated factor (PCAF), for which it has no activity, KAT5, KAT6B, and KAT7 (IC50s = >100, >100, and 84.82 µM, respectively), CREB-binding protein...
| Schlagworte: | 7-chloro-8-ethyl-10-[2-(2-methylpropoxy)ethyl]-benzo[g]pteridine-2,4(3H,10H)-dione |
| Anwendung: | Histone acetyltransferase 1 (HAT1) inhibitor |
| CAS | 2887480-87-5 |
| MW: | 376.8 D |
ab 116,00 €
