Zu "288383-20-0" wurden 3 Artikel gefunden!
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Cediranib
Artikelnummer: Cay11495-5
Receptors for VEGF have central roles in vasculogenesis and angiogenesis and thus serve as targets for cancer therapy. Cediranib is a potent inhibitor of VEGF receptor tyrosine kinases, including VEGFR1, 2, and 3 (IC50s = 5, 1, and 3 nM, respectively). It also potently inhibits a variety of other receptor and...
| Schlagworte: | AZD 2171, ZD 2171, 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-quinazoline |
| Anwendung: | VEGFR1/2/3 inhibitor |
| CAS | 288383-20-0 |
| MW: | 450.5 D |
ab 133,00 €
Cediranib
Artikelnummer: LKT-C1613.100
Cediranib is a potent antitumor and antiangiogenic compound. It inhibits vascular endotheial growth factor(VEGF) receptor tyrosine kinases.
| Schlagworte: | AZD2171 |
| Anwendung: | VEGF receptor tyrosine kinase inhibitor |
| CAS | 288383-20-0 |
| MW: | 450,51 D |
ab 202,00 €
Cediranib
Artikelnummer: TGM-T2500-100mg
Description: Cediranib (AZD2171) (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/=3 nM), similar activity against PDGFRbeta and c-Kit, selective more for VEGFR than PDGFR-alpha (36-fold), CSF-1R (110-fold), and...
| Schlagworte: | NSC-732208, AZD2171 |
| Anwendung: | Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1) |
| CAS | 288383-20-0 |
| MW: | 450.51 D |
ab 34,00 €
