Zu "288150-92-5" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
SB-408124
Artikelnummer: Cay22961-10
SB-408124 is a potent antagonist of orexin 1 receptors (OX1Rs) with a Ki value of 26.9 nM in a calcium mobilization assay using CHO cells that stably express human OX1R. It is selective for OX1R over OX2R, with Kd values of 21.7 and 1,704 nM, respectively, in a radioligand binding assay. In vivo co-perfusion of...
| Schlagworte: | N-(6,8-difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]-urea |
| Anwendung: | OX1R antagonist |
| CAS | 288150-92-5 |
| MW: | 356.4 D |
ab 126,00 €
SB-408124
Artikelnummer: TGM-T6658-10mg
Description: SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor. Target: OX Receptor. Smiles: CN(C)c1ccc(NC(=O)Nc2cc(C)nc3c(F)cc(F)cc23)cc1. References: Langmead CJ, et al, Br J Pharmacol,...
| Anwendung: | OX1R antagonist |
| CAS | 288150-92-5 |
| MW: | 356.37 D |
ab 39,00 €
