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OTX008
Artikelnummer: Cay23130-1
OTX008 is a small molecule topomimetic of the antiangiogenic peptide anginex and an inhibitor of galectin-1 (Gal-1). It decreases lactose binding to Gal-1 with Kd values of 290 and 100 µM in the presence and absence of OTX008, respectively, and is cytotoxic against a cancer cell panel with IC50 values that directly...
| Schlagworte: | Calixarene 0118, PTX008,... |
| Anwendung: | Galectin-1 inhibitor |
| CAS | 286936-40-1 |
| MW: | 937.2 D |
ab 102,00 €
OTX008
Artikelnummer: TGM-T16413-100mg
Description: OTX008 (PTX008) is a selective galectin-1 inhibitor. Target: Galectin. Smiles: O(CC(NCCN(C)C)=O)C=1C=2CC=3C(OCC(NCCN(C)C)=O)=C(CC=4C(OCC(NCCN(C)C)=O)=C(CC5=C(OCC(NCCN(C)C)=O)C(CC1C=CC2)=CC=C5)C=CC4)C=CC3. References: Astorgues-Xerri L, et al. OTX008, a selective small-molecule inhibitor of galectin-1,...
| Schlagworte: | PTX008, Calixarene 0118 |
| Anwendung: | Galectin-1 inhibitor |
| CAS | 286936-40-1 |
| MW: | 937.18 D |
ab 60,00 €
