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L-838,417
L-838,417

Artikelnummer: Cay22007-1

L-838,417 is a partial agonist of alpha2-, alpha3-, and alpha5 subunit-containing GABAA receptors. It potentiates GABA-induced currents in LTK- cells expressing alpha2beta3gamma2, alpha3beta3gamma2, or alpha5beta3gamma2 subunit-containing GABAA receptors when used at a concentration of 100 nM. In vivo, L-838,417 (10...
Schlagworte: 3-(2,5-difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine
Anwendung: alpha2/alpha3/alpha5 subunit-containing GABAA receptor partial agonist
CAS 286456-42-6
MW: 399.4 D
ab 73,00 €
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L-838417
L-838417

Artikelnummer: TGM-T19702-10mg

Description: L-838417 is a GABAA receptor subtype-selective benzodiazepine site-selective ligand and GABAA receptor-positive modulator.L-838417 is a selective partial agonist of the alpha2, alpha3, and alpha5 subtypes and an antagonist of the alpha1 subtype and is used in the study of anxiety disorders. Target: GABA...
Schlagworte: L838417 , L 838417
Anwendung: alpha2/alpha3/alpha5 subunit-containing GABAA receptor partial agonist
CAS 286456-42-6
MW: 399.4 D
ab 48,00 €
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