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A-286982
Artikelnummer: TGM-T21781-100mg
Description: A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1. Target: Integrin. Smiles: CC(C)c1ccccc1Sc1ccc(\C=C\C(=O)N2CCN(CC2)C(C)=O)cc1[N+]([O-])=O. References: Liu G, Link JT, Pei Z, et al....
| CAS | 280749-17-9 |
| MW: | 453.55 D |
ab 31,00 €
A286982
Artikelnummer: Cay27646-10
A286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1, IC50 = 35 nM). It inhibits adhesion of JY-8 cells to ICAM-1-coated microtiter plates (IC50 = 44 nM).Formal Name:...
| Schlagworte: | (2E)-1-(4-acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one |
| Anwendung: | ICAM-1:LFA-1 interaction inhibitor |
| CAS | 280749-17-9 |
| MW: | 453.6 D |
ab 90,00 €
