Zu "280744-09-4" wurden 3 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
SB-216763
Artikelnummer: Cay10010246-5
Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by an assortment of extracellular stimuli including insulin, growth factors, cell specification factors, and cell adhesion. SB-216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3alpha with an IC50...
| Schlagworte: | 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Anwendung: | GSK inhibitor |
| CAS | 280744-09-4 |
| MW: | 371.2 D |
ab 67,00 €
SB 216763
Artikelnummer: TGM-T3077-100mg
Description: SB 216763 (SB216763) is an effective and specific GSK-3alpha/beta inhibitor (IC50: 34.3 nM). Target: GSK-3, Autophagy. Smiles: O=C1C(C=2C=3C(N(C)C2)=CC=CC3)=C(C(=O)N1)C4=C(Cl)C=C(Cl)C=C4. References: Coghlan MP, et al. Chem Biol, 2000, 7(10), 793-803.
| Schlagworte: | SB216763 |
| Anwendung: | Potent selective cell permeable ATP-competitive inhibitor of GSK3 inhibitor |
| CAS | 280744-09-4 |
| MW: | 371.22 D |
ab 34,00 €
SB216763
Artikelnummer: AG-CR1-3659-M005
Solid. Soluble in DMSO (20mg/ml) or ethanol. Potent and selective cell permeable, ATP-competitive inhibitor of GSK3alpha with an IC50 value of 34nM (and similar potency for GSK3beta), DYRK1A inhibitor (IC50=0.8µM), Stimulates glycogen synthesis in liver cells and induces beta-catenin-dependent gene transcription,...
| Schlagworte: | 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Anwendung: | Potent selective cell permeable ATP-competitive inhibitor of GSK3 inhibitor |
| CAS | 280744-09-4 |
| MW: | 371,2 D |
ab 44,00 €
