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SB-216763
SB-216763

Artikelnummer: Cay10010246-5

Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by an assortment of extracellular stimuli including insulin, growth factors, cell specification factors, and cell adhesion. SB-216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3alpha with an IC50...
Schlagworte: 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Anwendung: GSK inhibitor
CAS 280744-09-4
MW: 371.2 D
ab 98,00 €
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SB216763
SB216763

Artikelnummer: AG-CR1-3659-M005

Solid. Soluble in DMSO (20mg/ml) or ethanol. Potent and selective cell permeable, ATP-competitive inhibitor of GSK3alpha with an IC50 value of 34nM (and similar potency for GSK3beta), DYRK1A inhibitor (IC50=0.8µM), Stimulates glycogen synthesis in liver cells and induces beta-catenin-dependent gene transcription,...
Schlagworte: 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Anwendung: Potent selective cell permeable ATP-competitive inhibitor of GSK3 inhibitor
CAS 280744-09-4
MW: 371,2 D
ab 39,00 €
Bewerten