Zu "2803881-11-8" wurden 2 Artikel gefunden!
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MRT2359
Artikelnummer: Cay44120-10
MRT2359 is a molecular glue degrader of G1 to S phase transition protein 1 homolog (GSPT1). It promotes the interaction between the E3 ubiquitin ligase cereblon and GSPT1, inducing the degradation of GSPT1 and termination of protein synthesis. InChI:...
| Schlagworte: | N-[2-fluoro-5-(trifluoromethoxy)phenyl]-carbamic acid, [2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-3-oxo-1H-isoindol-5-yl]... |
| Anwendung: | Molecular glue GSPT1 (ERF3A) degrader |
| CAS | 2803881-11-8 |
| MW: | 495.39 D |
ab 170,00 €
MRT-2359
Artikelnummer: TGM-T67934-100mg
Description: MRT-2359 is a potent and orally available GSPT1 reducer with antitumour activity.MRT-2359 inhibits the growth of drug-resistant non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) cells.MRT-2359 exhibits preferential activity in MYC-driven cell lines. Target: Apoptosis, Others. Smiles:...
| CAS | 2803881-11-8 |
| MW: | 495.38 D |
ab 48,00 €
