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AZD 5462
Artikelnummer: Cay40956-1
AZD 5462 is an agonist of relaxin family peptide receptor 1 (RXFP1). It induces cAMP mobilization in HEK293 cells expressing the human RXFP1 (EC50 = 15.85 nM). AZD 5462 increases heart rate and mean arterial blood pressure (MABP) in rats. It increases left ventricular ejection fraction (LVEF) in a cynomolgus monkey...
| Schlagworte: | cis-4-[2-fluoro-4-methoxy-5-[[[(1S,2R,3S,4R)-3-[[[(1-methylcyclobutyl)methyl]amino]carbonyl]bicyclo[2.2.1]hept-2-yl]amino]... |
| Anwendung: | RXFP1 agonist |
| CAS | 2787501-83-9 |
| MW: | 544.7 D |
ab 197,00 €
AZD5462
Artikelnummer: TGM-T63838-100mg
Description: AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer. Target: RXFP receptor. Smiles: C(NCC1(C)CCC1)(=O)[C@@H]2[C@H](NC(=O)C3=C(OC)C=C(F)C(O[C@H]4CC[C@](C(O)=O)(C)CC4)=C3)[C@@]5(C[C@]2(CC5)[H])[H]. References: Granberg Kenneth Lars, et al....
| Anwendung: | RXFP1 agonist |
| CAS | 2787501-83-9 |
| MW: | 544.65 D |
ab 352,00 €
