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PROTAC(H-PGDS)-7
Artikelnummer: Cay35561-1
PROTAC(H-PGDS)-7 is a proteolysis-targeting chimera (PROTAC) comprised of the hematopoietic prostaglandin D synthase (H-PGDS) inhibitor TFC-007 (Cay-17971) and the cereblon inhibitor pomalidomide (Cay-19877). It induces degradation of H-PGDS in KU812 cells with a 50% degradation concentration (DC50) value of 17.3...
| Schlagworte: | Proteolysis-targeting Chimera (Prostaglandin D Synthase (hematopoietic-type))-7,... |
| Anwendung: | PROTAC, H-PGDS degradation |
| CAS | 2761281-50-7 |
| MW: | 742.8 D |
ab 303,00 €
PROTAC(H-PGDS)-7
Artikelnummer: TGM-T41267-1mg
Description: PROTAC(H-PGDS)-7 is a selective and potent small molecule hematopoietic prostaglandin D synthase (H-PGDS) PROTAC degradation agent that exhibits degradation activity in KU812 cells with a DC50 of 17.3 pM. It effectively inhibits prostaglandin D2 (PGD2) and is a candidate compound for the treatment of...
| Anwendung: | PROTAC, H-PGDS degradation |
| CAS | 2761281-50-7 |
| MW: | 742.78 D |
ab 674,00 €
