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Gambogic Acid
Gambogic Acid

Artikelnummer: Cay14761-1

Gambogic acid (GA) is a xanthonoid that has been found in G. hanburyi resin and has anticancer activity. It binds covalently to the regulatory subunit B (SPTSSB) of the serine palmitoyltransferase complex (Ki = 1.5 µM, kinact = 0.05 min-1) and inhibits de novo sphingolipid biosynthesis. GA activates caspases in T47D...
Schlagworte: GA, beta-Guttiferin,...
Anwendung: Caspase activator
CAS 2752-65-0
MW: 628.8 D
ab 44,00 €
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Gambogic acid
Gambogic acid

Artikelnummer: LKT-G0248.100

Gambogic acid is a xanthonoid isolated from the brownish or orange resin from Garcinia hanburyi. Its anticancer activities are due to apoptosis induction, inhibition of topoisomerase and telomerase, and angiogenesis modification.
Schlagworte: 1,51,5-Methano-1H,3H,11H-furo(3,4-G)pyrano(3,2-B)xanthene-1-crotonic acid, B''-Guttiferrin, Beta-Guttiferrin,...
Anwendung: Apoptosis inducer
CAS 2752-65-0
MW: 628.75 D
ab 170,00 €
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