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Luxdegalutamide
Artikelnummer: TGM-T75129-100mg
Description: Luxdegalutamide (ARV-766) is an orally available and effective protein degrader of protein hydrolysis-targeted chimeras (PROTAC).Luxdegalutamide degrades the wild-type androgen receptor AR, as well as AR LBD mutants including those associated with the most prevalent pathogenic AR L702H, H875Y and T878A...
| Schlagworte: | ARV-766 |
| CAS | 2750830-09-0 |
| MW: | 807.95 D |
ab 300,00 €
ARV-766
Artikelnummer: Cay41985-1
A PROTAC that drives androgen receptor degradation (DC50 = <1 nM), inhibits tumor growth in various LNCaP and VCaP prostate cancer mouse xenograft models, including an enzalutamide-insensitive, non-castrated VCaP model. Formulation: A solid. InChI:...
| Schlagworte: | Luxdegalutamide,... |
| Anwendung: | Androgen receptor degradation driving PROTAC |
| CAS | 2750830-09-0 |
| MW: | 807.95 D |
ab 119,00 €
