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MCUF-651
Artikelnummer: TGM-T67734-100mg
Description: MCUF-651 is a guanylyl cyclase A receptor positive allosteric modulators, EC50=0.45 µM. Target: Guanylate cyclase. Smiles: FC1=C2C(SC(NC(=O)C3CN(CCN(C)C)CCC3)=N2)=CC(F)=C1. References: Sangaralingham SJ, et al. Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators. Proc...
| CAS | 2747162-85-0 |
| MW: | 368.44 D |
ab 53,00 €
MCUF-651
Artikelnummer: Cay42055-10
A GC-A positive allosteric modulator, induces the production of cGMP in the presence (EC50 = 0.45 µM) but not the absence of ANP in HEK293 cells expressing human GC-A, selective for GC-A over GC-B in HEK293 cells expressing the human receptors at 10 µM, binds to the GC-A extracellular domain (Kd = 397 nM) and...
| Schlagworte: | N-(4,6-difluoro-2-benzothiazolyl)-1-[2-(dimethylamino)ethyl]-3-piperidinecarboxamide |
| Anwendung: | GC-A positive allosteric modulator |
| CAS | 2747162-85-0 |
| MW: | 368.45 D |
ab 193,00 €
