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Thiocolchicine
Thiocolchicine

Artikelnummer: TGM-T41248-100mg

Description: Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 µM and a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology. Target: Microtubule Associated. Smiles:...
Anwendung: Apoptosis Inducer
CAS 2730-71-4
MW: 415.5 D
ab 42,00 €
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Thiocolchicine
Thiocolchicine

Artikelnummer: Cay17427-10

Thiocolchicine is an inhibitor of microtubule assembly (IC50 = 2.5 µM) and a derivative of colchicine (Cay-9000760). It inhibits binding of colchicine to tubulin (Ki = 0.7 µM in a radioligand binding assay). Thiocolchicine inhibits proliferation of MDA-MB-231 and multidrug resistant (MDR) MCF-7 ADRr breast cancer...
Schlagworte: NSC 186301, N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-acetamide
Anwendung: Tubulin polymerization inhibitor, Topo I inhibitor, apoptosis inducer
CAS 2730-71-4
MW: 415.5 D
ab 53,00 €
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Thiocolchicine
Thiocolchicine

Artikelnummer: AG-CN2-0074-M005

Antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor. Axonal cytoskeleton modulator. Apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors.
Schlagworte: 10-Demethoxy-10-methylthiocolchicine, NSC 186301
Anwendung: Apoptosis Inducer
Wirt: Semisynthetic
CAS 2730-71-4
MW: 415,5 D
ab 39,00 €
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