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NEU
Zongertinib
Artikelnummer: Cay44994-10
Zongertinib is an inhibitor of mutant HER2 containing an activating exon 20 insertion (HER2YVMA. IC50 = 13 nM in a cellular phosphorylation assay using HEK cells). It is selective for the inhibition of HER2YVMA over wild-type EGFR (IC50 = 576 nM in a cellular phosphorylation assay using HEK cells). It is also...
| Schlagworte: | BI 1810631,... |
| Anwendung: | HER2-YVMA inhibitor |
| CAS | 2728667-27-2 |
| MW: | 535.61 D |
ab 134,00 €
Zongertinib
Artikelnummer: TGM-T69534-10mg
Description: Zongertinib is a human HER2-selective tyrosine kinase inhibitor, a novel TK that is highly selective for covalent binding to the HER2 tyrosine kinase domain (TKD).Zongertinib exhibits antitumor activity with inhibitory effects on pHER2 and EGF. Target: Tyrosine Kinases, HER. Smiles:...
| Schlagworte: | BI 1810631, BI 764532 |
| Anwendung: | Targets receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1] (ERBB2, HER2, CD340) |
| CAS | 2728667-27-2 |
| MW: | 535.6 D |
ab 65,00 €
