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RPI-1
Artikelnummer: Cay20384-10
RPI-1 is an ATP-dependent RET kinase inhibitor. It has been shown to selectively inhibit the anchorage-independent growth of NIH3T3 cells transformed by the ret/ptc1 oncogene with an IC50 value of 0.97 µM. In a spontaneously metastasizing lung carcinoma xenograft mouse model, daily oral treatment with RPI-1 was...
| Schlagworte: | 1,3-dihydro-3-[(4-hydroxyphenyl)methylene]-5,6-dimethoxy-2H-indol-2-one |
| Anwendung: | ATP-dependent RET kinase inhibitor |
| CAS | 269730-03-2 |
| MW: | 297.3 D |
ab 49,00 €
RPI-1
Artikelnummer: TGM-T2282-100mg
Description: RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor. Target: c-Met/HGFR, c-RET, Phospholipase, Others. Smiles: COc1cc2NC(=O)\C(=C/c3ccc(O)cc3)c2cc1OC. References: Petrangolini G, et al. Biochem Pharmacol. 2006 Aug 14,72(4):405-14. 2. Caccia D, et al. Mol Y. 2010 Oct 18,9:278.
| CAS | 269730-03-2 |
| MW: | 297.31 D |
ab 45,00 €
