Zu "2660250-10-0" wurden 2 Artikel gefunden!
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BLU-945
Artikelnummer: TGM-T9754-100mg
Description: BLU-945 is a reversible, potent, highly selective, and orally available epidermal growth factor receptor tyrosine kinase inhibitor (TKIs). BLU-945 inhibits EGFR phosphorylation in EGFR L858R/T790M/C797S and EGFR ex19del/T790M/C797S mutant cell lines. BLU-945 can be used in lung cancer research,...
| Schlagworte: | BLU945 , BLU 945 |
| Anwendung: | Targets epidermal growth factor receptor [EC:2.7.10.1] (EGFR, ERBB1) |
| CAS | 2660250-10-0 |
| MW: | 556.7 D |
ab 31,00 €
BLU-945
Artikelnummer: Cay43015-10
BLU-945 is an inhibitor of mutant EGFR (IC50s = 0. and 0. nM for EGFRL858R/T790M and EGFRL858R/T790M/C797S, respectively). It is selective for these mutants over wild-type EGFR (IC50 = 683 nM) and a panel of greater than 400 kinases at 3 µM. In vivo, BLU-945 (100 mg/kg) induces tumor regression in a mouse xenograft...
| Schlagworte: | Tigozertinib,... |
| Anwendung: | Mutant EGFR inhibitor |
| CAS | 2660250-10-0 |
| MW: | 556.7 D |
ab 137,00 €
