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Endovion
Endovion

Artikelnummer: TGM-T15233-100mg

Description: Endovion (NS3728) is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is also the specific VRAC/VSOAC blocker. Target: Chloride channel. Smiles: FC(F)(F)c1cc(NC(=O)Nc2ccc(Br)cc2-c2nn[nH]n2)cc(c1)C(F)(F)F. References: Sørensen BH, et al. Downregulation of LRRC8A...
Schlagworte: NS3728
Anwendung: Chloride channel inhibitor
CAS 265646-85-3
MW: 495.18 D
ab 31,00 €
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NS 3728
NS 3728

Artikelnummer: Cay39988-10

NS 3728 is a chloride channel inhibitor. It inhibits the volume-regulated anion channel (VRAC) in HEK293 cells and chloride conductance in washed isolated human erythrocytes (IC50s = 0.4 and 0.6 µM, respectively). NS 3728 also inhibits calcium-activated chloride currents in Ehrlich-Lettre ascites carcinoma cells...
Schlagworte: Endovion, SCO 101, N-[3,5-bis(trifluoromethyl)phenyl]-N'-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-urea
Anwendung: Chloride channel inhibitor
CAS 265646-85-3
MW: 495.2 D
ab 136,00 €
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